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WABI
2001
Springer
110views Bioinformatics» more  WABI 2001»
14 years 28 days ago
Boosting EM for Radiation Hybrid and Genetic Mapping
Radiation hybrid (RH) mapping is a somatic cell technique that is used for ordering markers along a chromosome and estimating physical distances between them. It nicely complements...
Thomas Schiex, Patrick Chabrier, Martin Bouchez, D...
GPEM
2007
119views more  GPEM 2007»
13 years 8 months ago
Genomic mining for complex disease traits with "random chemistry"
Our rapidly growing knowledge regarding genetic variation in the human genome offers great potential for understanding the genetic etiology of disease. This, in turn, could revolut...
Margaret J. Eppstein, Joshua L. Payne, Bill C. Whi...
GECCO
2006
Springer
220views Optimization» more  GECCO 2006»
14 years 4 days ago
Comparing evolutionary algorithms on the problem of network inference
In this paper, we address the problem of finding gene regulatory networks from experimental DNA microarray data. We focus on the evaluation of the performance of different evoluti...
Christian Spieth, Rene Worzischek, Felix Streicher...
KDD
2001
ACM
142views Data Mining» more  KDD 2001»
14 years 9 months ago
TreeDT: gene mapping by tree disequilibrium test
We introduce and evaluate TreeDT, a novel gene mapping method which is based on discovering and assessing tree-like patterns in genetic marker data. Gene mapping aims at discoveri...
Petteri Sevon, Hannu Toivonen, Vesa Ollikainen
BMCBI
2005
80views more  BMCBI 2005»
13 years 8 months ago
Sample phenotype clusters in high-density oligonucleotide microarray data sets are revealed using Isomap, a nonlinear algorithm
Background: Life processes are determined by the organism's genetic profile and multiple environmental variables. However the interaction between these factors is inherently ...
Kevin Dawson, Raymond L. Rodriguez, Wasyl Malyj