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» The Proportional Genetic Algorithm: Gene Expression in a Gen...
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136
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GECCO
2008
Springer
148views Optimization» more  GECCO 2008»
15 years 4 months ago
Using quotient graphs to model neutrality in evolutionary search
We introduce quotient graphs for modeling neutrality in evolutionary search. We demonstrate that for a variety of evolutionary computing problems, search can be characterized by g...
Dominic Wilson, Devinder Kaur
126
Voted
CONSTRAINTS
2008
78views more  CONSTRAINTS 2008»
15 years 3 months ago
Boosting Haplotype Inference with Local Search
Abstract. A very challenging problem in the genetics domain is to infer haplotypes from genotypes. This process is expected to identify genes affecting health, disease and response...
Inês Lynce, João Marques-Silva, Steve...
132
Voted
BMCBI
2006
115views more  BMCBI 2006»
15 years 3 months ago
Detecting recombination in evolving nucleotide sequences
Background: Genetic recombination can produce heterogeneous phylogenetic histories within a set of homologous genes. These recombination events can be obscured by subsequent resid...
Cheong Xin Chan, Robert G. Beiko, Mark A. Ragan
153
Voted
BMCBI
2008
132views more  BMCBI 2008»
15 years 3 months ago
The SeqWord Genome Browser: an online tool for the identification and visualization of atypical regions of bacterial genomes thr
Background: Data mining in large DNA sequences is a major challenge in microbial genomics and bioinformatics. Oligonucleotide usage (OU) patterns provide a wealth of information f...
Hamilton Ganesan, Anna S. Rakitianskaia, Colin F. ...
BMCBI
2008
135views more  BMCBI 2008»
15 years 3 months ago
Inferring the role of transcription factors in regulatory networks
Background: Expression profiles obtained from multiple perturbation experiments are increasingly used to reconstruct transcriptional regulatory networks, from well studied, simple...
Philippe Veber, Carito Guziolowski, Michel Le Borg...