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TCBB
2010
80views more  TCBB 2010»
13 years 8 months ago
On the Importance of Comprehensible Classification Models for Protein Function Prediction
—The literature on protein function prediction is currently dominated by works aimed at maximizing predictive accuracy, ignoring the important issues of validation and interpreta...
Alex Alves Freitas, Daniela Wieser, Rolf Apweiler
LION
2009
Springer
112views Optimization» more  LION 2009»
14 years 4 months ago
A Graph-Based Semi-supervised Algorithm for Protein Function Prediction from Interaction Maps
Abstract. Protein function prediction represents a fundamental challenge in bioinformatics. The increasing availability of proteomics network data has enabled the development of se...
Valerio Freschi
BIRD
2007
Springer
112views Bioinformatics» more  BIRD 2007»
14 years 4 months ago
Patch Prediction of Protein Interaction Sites: Validation of a Scoring Function for an Online Server
An online protein interaction server has been designed and implemented to make predictions for 256 nonhomologous protein-protein interaction sites using patch analysis. Predictions...
Susan Jones, Yoichi Mukarami
IDEAL
2005
Springer
14 years 3 months ago
Exploiting Sequence Dependencies in the Prediction of Peroxisomal Proteins
Prediction of peroxisomal matrix proteins generally depends on the presence of one of two distinct motifs at the end of the amino acid sequence. PTS1 peroxisomal proteins have a we...
Mark Wakabayashi, John Hawkins, Stefan Maetschke, ...
BIOCOMP
2010
13 years 8 months ago
Extraction of Protein Sequence Motifs Information by Bi-Clustering Algorithm
- The activities and function of proteins can potentially be determined by protein sequence motifs. Therefore, obtaining the universally conserved and crossed protein family bounda...
Vincent Yip, Bernard Chen, Sinan Kockara