Background: Elucidating the dynamic behaviour of genetic regulatory networks is one of the most significant challenges in systems biology. However, conventional quantitative predi...
RNA interference (RNAi) has become a powerful tool for genetic screening in Drosophila. At the Drosophila RNAi Screening Center (DRSC), we are using a library of over 21 000 doubl...
Ian Flockhart, Matthew Booker, Amy Kiger, Michael ...
The noncoding RNAs and protein related biomacromolecules interaction database (NPInter; http:// bioinfo.ibp.ac.cn/NPInter or http://www.bioinfo.org. cn/NPInter) is a database that...
Tao Wu, Jie Wang, Changning Liu, Yong Zhang, Baoch...
Recently, profile context-sensitive HMMs (profile-csHMMs) have been proposed which are very effective in modeling the common patterns and motifs in related symbol sequences. Pro...
Understanding the functional significance of alternative splicing and other mechanisms that generate RNA transcript diversity is an important challenge facing modern-day molecular...
Ann E. Loraine, Gregg A. Helt, Melissa S. Cline, M...