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BMCBI
2010
117views more  BMCBI 2010»
13 years 8 months ago
Beyond rotamers: a generative, probabilistic model of side chains in proteins
Background: Accurately covering the conformational space of amino acid side chains is essential for important applications such as protein design, docking and high resolution stru...
Tim Harder, Wouter Boomsma, Martin Paluszewski, Je...
BMCBI
2008
106views more  BMCBI 2008»
13 years 8 months ago
An Integrated Korean Biodiversity and Genetic Information Retrieval System
Background: On-line biodiversity information databases are growing quickly and being integrated into general bioinformatics systems due to the advances of fast gene sequencing tec...
Jeongheui Lim, Jong Bhak, Hee-Mock Oh, Chang-Bae K...
IANDC
2008
92views more  IANDC 2008»
13 years 8 months ago
Tree exploration with advice
We study the amount of knowledge about the network that is required in order to efficiently solve a task concerning this network. The impact of available information on the effici...
Pierre Fraigniaud, David Ilcinkas, Andrzej Pelc
BMCBI
2006
194views more  BMCBI 2006»
13 years 8 months ago
Novel metaheuristic for parameter estimation in nonlinear dynamic biological systems
Background: We consider the problem of parameter estimation (model calibration) in nonlinear dynamic models of biological systems. Due to the frequent ill-conditioning and multi-m...
Maria Rodriguez-Fernandez, Jose A. Egea, Julio R. ...
CACM
2006
102views more  CACM 2006»
13 years 8 months ago
Infoglut
whose titles and abstracts sound very interesting, the pile of unread reports continues to grow on the table in my office." (How quaint the terminology: mail and electronic me...
Peter J. Denning