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BMCBI
2010
82views more  BMCBI 2010»
13 years 8 months ago
SolexaQA: At-a-glance quality assessment of Illumina second-generation sequencing data
Background: Illumina's second-generation sequencing platform is playing an increasingly prominent role in modern DNA and RNA sequencing efforts. However, rapid, simple, stand...
Murray P. Cox, Daniel A. Peterson, Patrick J. Bigg...
BMCBI
2010
118views more  BMCBI 2010»
13 years 8 months ago
Bacillus anthracis genome organization in light of whole transcriptome sequencing
Emerging knowledge of whole prokaryotic transcriptomes could validate a number of theoretical concepts introduced in the early days of genomics. What are the rules connecting gene...
Jeffrey Martin, Wenhan Zhu, Karla D. Passalacqua, ...
CLUSTER
2003
IEEE
14 years 1 months ago
A Case Study of Parallel I/O for Biological Sequence Search on Linux Clusters
In this paper we analyze the I/O access patterns of a widely-used biological sequence search tool and implement two variations that employ parallel-I/O for data access based on PV...
Yifeng Zhu, Hong Jiang, Xiao Qin, David R. Swanson
WABI
2009
Springer
156views Bioinformatics» more  WABI 2009»
14 years 3 months ago
Phylogenetic Comparative Assembly
Recent high throughput sequencing technologies are capable of generating a huge amount of data for bacterial genome sequencing projects. Although current sequence assemblers succes...
Peter Husemann, Jens Stoye
BMCBI
2006
117views more  BMCBI 2006»
13 years 8 months ago
Gene Designer: a synthetic biology tool for constructing artificial DNA segments
Background: Direct synthesis of genes is rapidly becoming the most efficient way to make functional genetic constructs and enables applications such as codon optimization, RNAi re...
Alan Villalobos, Jon E. Ness, Claes Gustafsson, Je...