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» The Spatially-Dispersed Genetic Algorithm
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BMCBI
2006
108views more  BMCBI 2006»
13 years 7 months ago
An improved map of conserved regulatory sites for Saccharomyces cerevisiae
Background: The regulatory map of a genome consists of the binding sites for proteins that determine the transcription of nearby genes. An initial regulatory map for S. cerevisiae...
Kenzie D. MacIsaac, Ting Wang, D. Benjamin Gordon,...
BMCBI
2006
175views more  BMCBI 2006»
13 years 7 months ago
Parameter estimation for stiff equations of biosystems using radial basis function networks
Background: The modeling of dynamic systems requires estimating kinetic parameters from experimentally measured time-courses. Conventional global optimization methods used for par...
Yoshiya Matsubara, Shinichi Kikuchi, Masahiro Sugi...
BMCBI
2006
86views more  BMCBI 2006»
13 years 7 months ago
Microbial identification by mass cataloging
Background: The public availability of over 180,000 bacterial 16S ribosomal RNA (rRNA) sequences has facilitated microbial identification and classification using hybridization an...
Zhengdong Zhang, George W. Jackson, George E. Fox,...
BMCBI
2006
130views more  BMCBI 2006»
13 years 7 months ago
MicroTar: predicting microRNA targets from RNA duplexes
Background: The accurate prediction of a comprehensive set of messenger RNAs (targets) regulated by animal microRNAs (miRNAs) remains an open problem. In particular, the predictio...
Rahul Thadani, Martti T. Tammi
BMCBI
2006
113views more  BMCBI 2006»
13 years 7 months ago
QualitySNP: a pipeline for detecting single nucleotide polymorphisms and insertions/deletions in EST data from diploid and polyp
Background: Single nucleotide polymorphisms (SNPs) are important tools in studying complex genetic traits and genome evolution. Computational strategies for SNP discovery make use...
Jifeng Tang, Ben Vosman, Roeland E. Voorrips, C. G...