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BMCBI
2010
106views more  BMCBI 2010»
15 years 4 months ago
TumorBoost: Normalization of allele-specific tumor copy numbers from a single pair of tumor-normal genotyping microarrays
Background: High-throughput genotyping microarrays assess both total DNA copy number and allelic composition, which makes them a tool of choice for copy number studies in cancer, ...
Henrik Bengtsson, Pierre Neuvial, Terence P. Speed
BMCBI
2010
143views more  BMCBI 2010»
15 years 4 months ago
Learning gene regulatory networks from only positive and unlabeled data
Background: Recently, supervised learning methods have been exploited to reconstruct gene regulatory networks from gene expression data. The reconstruction of a network is modeled...
Luigi Cerulo, Charles Elkan, Michele Ceccarelli
BMCBI
2010
118views more  BMCBI 2010»
15 years 4 months ago
Artificial neural networks for the prediction of peptide drift time in ion mobility mass spectrometry
Background: There is an increasing usage of ion mobility-mass spectrometry (IMMS) in proteomics. IMMS combines the features of ion mobility spectrometry (IMS) and mass spectrometr...
Bing Wang, Steve Valentine, Manolo Plasencia, Srir...
BMCBI
2010
86views more  BMCBI 2010»
15 years 4 months ago
Fast motif recognition via application of statistical thresholds
Background: Improving the accuracy and efficiency of motif recognition is an important computational challenge that has application to detecting transcription factor binding sites...
Christina Boucher, James King
BMCBI
2008
219views more  BMCBI 2008»
15 years 4 months ago
Classification of premalignant pancreatic cancer mass-spectrometry data using decision tree ensembles
Background: Pancreatic cancer is the fourth leading cause of cancer death in the United States. Consequently, identification of clinically relevant biomarkers for the early detect...
Guangtao Ge, G. William Wong
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