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FUIN
2008
119views more  FUIN 2008»
15 years 4 months ago
Modeling Communication with Synchronized Environments
A deterministic behavior of systems composed of several modules is a desirable design goal. Assembling a complex system from components requires also a high degree of re-usability....
Tiberiu Seceleanu, Axel Jantsch
BMCBI
2006
122views more  BMCBI 2006»
15 years 4 months ago
A domain-oriented approach to the reduction of combinatorial complexity in signal transduction networks
Background:Receptors and scaffold proteins possess a number of distinct domains and bind multiple partners. A common problem in modeling signaling systems arises from a combinator...
Holger Conzelmann, Julio Saez-Rodriguez, Thomas Sa...
GPEM
2008
98views more  GPEM 2008»
15 years 4 months ago
Sporadic model building for efficiency enhancement of the hierarchical BOA
Efficiency enhancement techniques--such as parallelization and hybridization--are among the most important ingredients of practical applications of genetic and evolutionary algori...
Martin Pelikan, Kumara Sastry, David E. Goldberg
BMCBI
2006
179views more  BMCBI 2006»
15 years 4 months ago
Multiscale Hy3S: Hybrid stochastic simulation for supercomputers
Background: Stochastic simulation has become a useful tool to both study natural biological systems and design new synthetic ones. By capturing the intrinsic molecular fluctuation...
Howard Salis, Vassilios Sotiropoulos, Yiannis N. K...
BMCBI
2006
156views more  BMCBI 2006»
15 years 4 months ago
Score-based prediction of genomic islands in prokaryotic genomes using hidden Markov models
Background: Horizontal gene transfer (HGT) is considered a strong evolutionary force shaping the content of microbial genomes in a substantial manner. It is the difference in spee...
Stephan Waack, Oliver Keller, Roman Asper, Thomas ...
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