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BMCBI
2008
118views more  BMCBI 2008»
15 years 4 months ago
Virtual screening of GPCRs: An in silico chemogenomics approach
The G-protein coupled receptor (GPCR) superfamily is currently the largest class of therapeutic targets. In silico prediction of interactions between GPCRs and small molecules is ...
Laurent Jacob, Brice Hoffmann, Véronique St...
JCSS
2008
90views more  JCSS 2008»
15 years 4 months ago
Fault tolerance in cellular automata at high fault rates
A commonly used model for fault-tolerant computation is that of cellular automata. The essential difficulty of fault-tolerant computation is present in the special case of simply ...
Mark McCann, Nicholas Pippenger
JMIV
2006
91views more  JMIV 2006»
15 years 4 months ago
Harmonic Embeddings for Linear Shape Analysis
We present a novel representation of shape for closed contours in R2 or for compact surfaces in R3 explicitly designed to possess a linear structure. This greatly simplifies linear...
Alessandro Duci, Anthony J. Yezzi, Stefano Soatto,...
169
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EOR
2007
165views more  EOR 2007»
15 years 4 months ago
Adaptive credit scoring with kernel learning methods
Credit scoring is a method of modelling potential risk of credit applications. Traditionally, logistic regression, linear regression and discriminant analysis are the most popular...
Yingxu Yang
169
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SIAMSC
2008
149views more  SIAMSC 2008»
15 years 4 months ago
Adaptive Discrete Galerkin Methods Applied to the Chemical Master Equation
In systems biology, the stochastic description of biochemical reaction kinetics is increasingly being employed to model gene regulatory networks and signalling pathways. Mathematic...
Peter Deuflhard, Wilhelm Huisinga, T. Jahnke, Mich...
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