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BMCBI
2008
144views more  BMCBI 2008»
13 years 8 months ago
Pep-3D-Search: a method for B-cell epitope prediction based on mimotope analysis
Background: The prediction of conformational B-cell epitopes is one of the most important goals in immunoinformatics. The solution to this problem, even if approximate, would help...
Yanxin Huang, Yongli Bao, Shu Yan Guo, Yan Wang, C...
BMCBI
2008
77views more  BMCBI 2008»
13 years 8 months ago
SeqAn An efficient, generic C++ library for sequence analysis
Background: The use of novel algorithmic techniques is pivotal to many important problems in life science. For example the sequencing of the human genome [1] would not have been p...
Andreas Döring, David Weese, Tobias Rausch, K...
BMCBI
2008
86views more  BMCBI 2008»
13 years 8 months ago
Subfamily specific conservation profiles for proteins based on n-gram patterns
Background: A new algorithm has been developed for generating conservation profiles that reflect the evolutionary history of the subfamily associated with a query sequence. It is ...
John K. Vries, Xiong Liu
BMCBI
2008
164views more  BMCBI 2008»
13 years 8 months ago
Word correlation matrices for protein sequence analysis and remote homology detection
Background: Classification of protein sequences is a central problem in computational biology. Currently, among computational methods discriminative kernel-based approaches provid...
Thomas Lingner, Peter Meinicke
BMCBI
2008
85views more  BMCBI 2008»
13 years 8 months ago
Normalizing biomedical terms by minimizing ambiguity and variability
Background: One of the difficulties in mapping biomedical named entities, e.g. genes, proteins, chemicals and diseases, to their concept identifiers stems from the potential varia...
Yoshimasa Tsuruoka, John McNaught, Sophia Ananiado...
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