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CBMS
2007
IEEE
14 years 4 months ago
An Unsupervised and Fully-Automated Image Analysis Method for cDNA Microarrays
Microarray gene expression image analysis is a labor-intensive task and requires human intervention since microarray images are contaminated with noise and artifacts while spots a...
Eleni Zacharia, Dimitrios E. Maroulis
EVOW
2004
Springer
14 years 3 months ago
Iteratively Inferring Gene Regulatory Networks with Virtual Knockout Experiments
Abstract. In this paper we address the problem of finding gene regulatory networks from experimental DNA microarray data. We introduce enhancements to an Evolutionary Algorithm op...
Christian Spieth, Felix Streichert, Nora Speer, An...
DNA
2005
Springer
14 years 3 months ago
Two Proteins for the Price of One: The Design of Maximally Compressed Coding Sequences
Abstract. The emerging field of synthetic biology moves beyond conventional genetic manipulation to construct novel life forms which do not originate in nature. We explore the pro...
Bei Wang, Dimitris Papamichail, Steffen Mueller, S...
BMCBI
2006
99views more  BMCBI 2006»
13 years 10 months ago
Genetic algorithm learning as a robust approach to RNA editing site prediction
Background: RNA editing is one of several post-transcriptional modifications that may contribute to organismal complexity in the face of limited gene complement in a genome. One f...
James Thompson, Shuba Gopal
BMCBI
2005
87views more  BMCBI 2005»
13 years 9 months ago
Efficient decoding algorithms for generalized hidden Markov model gene finders
Background: The Generalized Hidden Markov Model (GHMM) has proven a useful framework for the task of computational gene prediction in eukaryotic genomes, due to its flexibility an...
William H. Majoros, Mihaela Pertea, Arthur L. Delc...