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GECCO
2009
Springer
14 years 5 months ago
Multiobjectivization for parameter estimation: a case-study on the segment polarity network of drosophila
Mathematical modeling for gene regulative networks (GRNs) provides an effective tool for hypothesis testing in biology. A necessary step in setting up such models is the estimati...
Tim Hohm, Eckart Zitzler
CIKM
2006
Springer
14 years 2 months ago
Validating associations in biological databases
To cope with the large amount of biological sequences being produced, a significant number of genes and proteins have been annotated by automated tools. A protein annotation is an...
Francisco M. Couto, Mário J. Silva, Pedro C...
BMCBI
2008
186views more  BMCBI 2008»
13 years 11 months ago
Variable selection for large p small n regression models with incomplete data: Mapping QTL with epistases
Background: Identifying quantitative trait loci (QTL) for both additive and epistatic effects raises the statistical issue of selecting variables from a large number of candidates...
Min Zhang, Dabao Zhang, Martin T. Wells
BMCBI
2006
108views more  BMCBI 2006»
13 years 11 months ago
An improved map of conserved regulatory sites for Saccharomyces cerevisiae
Background: The regulatory map of a genome consists of the binding sites for proteins that determine the transcription of nearby genes. An initial regulatory map for S. cerevisiae...
Kenzie D. MacIsaac, Ting Wang, D. Benjamin Gordon,...
BMCBI
2006
130views more  BMCBI 2006»
13 years 11 months ago
MicroTar: predicting microRNA targets from RNA duplexes
Background: The accurate prediction of a comprehensive set of messenger RNAs (targets) regulated by animal microRNAs (miRNAs) remains an open problem. In particular, the predictio...
Rahul Thadani, Martti T. Tammi