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BMCBI
2008
149views more  BMCBI 2008»
13 years 7 months ago
Clustering of cognate proteins among distinct proteomes derived from multiple links to a single seed sequence
Background: Modern proteomes evolved by modification of pre-existing ones. It is extremely important to comparative biology that related proteins be identified as members of the s...
Adriano Barbosa-Silva, Venkata P. Satagopam, Reinh...
BMCBI
2008
135views more  BMCBI 2008»
13 years 7 months ago
Fregene: Simulation of realistic sequence-level data in populations and ascertained samples
Background: FREGENE simulates sequence-level data over large genomic regions in large populations. Because, unlike coalescent simulators, it works forwards through time, it allows...
Marc Chadeau-Hyam, Clive J. Hoggart, Paul F. O'Rei...
BMCBI
2005
120views more  BMCBI 2005»
13 years 7 months ago
SpectralNET - an application for spectral graph analysis and visualization
Background: Graph theory provides a computational framework for modeling a variety of datasets including those emerging from genomics, proteomics, and chemical genetics. Networks ...
Joshua J. Forman, Paul A. Clemons, Stuart L. Schre...
BMCBI
2004
114views more  BMCBI 2004»
13 years 7 months ago
HMM Logos for visualization of protein families
Background: Profile Hidden Markov Models (pHMMs) are a widely used tool for protein family research. Up to now, however, there exists no method to visualize all of their central a...
Benjamin Schuster-Böckler, Jörg Schultz,...
COMPUTER
2002
103views more  COMPUTER 2002»
13 years 7 months ago
SimpleScalar: An Infrastructure for Computer System Modeling
tail defines the level of abstraction used to implement the model's components. A highly detailed model will faithfully simulate all aspects of machine operation, whether or n...
Todd M. Austin, Eric Larson, Dan Ernst