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BMCBI
2006
137views more  BMCBI 2006»
13 years 8 months ago
Cell_motility: a cross-platform, open source application for the study of cell motion paths
Background: Migration is an important aspect of cellular behaviour and is therefore widely studied in cell biology. Numerous components are known to participate in this process in...
Lennart Martens, Geert Monsieur, Christophe Ampe, ...
BMCBI
2006
117views more  BMCBI 2006»
13 years 8 months ago
Gene Designer: a synthetic biology tool for constructing artificial DNA segments
Background: Direct synthesis of genes is rapidly becoming the most efficient way to make functional genetic constructs and enables applications such as codon optimization, RNAi re...
Alan Villalobos, Jon E. Ness, Claes Gustafsson, Je...
BMCBI
2006
116views more  BMCBI 2006»
13 years 8 months ago
MICA: desktop software for comprehensive searching of DNA databases
Background: Molecular biologists work with DNA databases that often include entire genomes. A common requirement is to search a DNA database to find exact matches for a nondegener...
William A. Stokes, Benjamin S. Glick
BMCBI
2006
100views more  BMCBI 2006»
13 years 8 months ago
Empirical array quality weights in the analysis of microarray data
Background: Assessment of array quality is an essential step in the analysis of data from microarray experiments. Once detected, less reliable arrays are typically excluded or &qu...
Matthew E. Ritchie, Dileepa S. Diyagama, Jody Neil...
BMCBI
2006
113views more  BMCBI 2006»
13 years 8 months ago
GibbsST: a Gibbs sampling method for motif discovery with enhanced resistance to local optima
Background: Computational discovery of transcription factor binding sites (TFBS) is a challenging but important problem of bioinformatics. In this study, improvement of a Gibbs sa...
Kazuhito Shida
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