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» The elastic net algorithm and protein structure prediction
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JCB
2006
215views more  JCB 2006»
13 years 7 months ago
Protein Fold Recognition Using Segmentation Conditional Random Fields (SCRFs)
Protein fold recognition is an important step towards understanding protein three-dimensional structures and their functions. A conditional graphical model, i.e., segmentation con...
Yan Liu 0002, Jaime G. Carbonell, Peter Weigele, V...
BMCBI
2010
139views more  BMCBI 2010»
13 years 7 months ago
MOTIPS: Automated Motif Analysis for Predicting Targets of Modular Protein Domains
Background: Many protein interactions, especially those involved in signaling, involve short linear motifs consisting of 5-10 amino acid residues that interact with modular protei...
Hugo Y. K. Lam, Philip M. Kim, Janine Mok, Raffi T...
JCB
2000
90views more  JCB 2000»
13 years 7 months ago
Geometric Invariant Core for the CL and CH1 Domains of Immunoglobulin Molecules
A previously developed algorithmic method for identifying a geometric invariant of protein structures, termed geometrical core, is extended to the and 1 domains of immunoglobulin ...
Ognyan Stoyanov, Alexander Kister, Israel Gelfand,...
BMCBI
2006
98views more  BMCBI 2006»
13 years 7 months ago
Optimised amino acid specific weighting factors for unbound protein docking
Background: One of the most challenging aspects of protein-protein docking is the inclusion of flexibility into the docking procedure. We developed a postfilter where the grid-rep...
Philipp Heuser, Dietmar Schomburg
BMCBI
2005
92views more  BMCBI 2005»
13 years 7 months ago
Predicting functional sites with an automated algorithm suitable for heterogeneous datasets
Background: In a previous report (La et al., Proteins, 2005), we have demonstrated that the identification of phylogenetic motifs, protein sequence fragments conserving the overal...
David La, Dennis R. Livesay