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BMCBI
2008
148views more  BMCBI 2008»
13 years 11 months ago
Critical assessment of alignment procedures for LC-MS proteomics and metabolomics measurements
Background: Liquid chromatography coupled to mass spectrometry (LC-MS) has become a prominent tool for the analysis of complex proteomics and metabolomics samples. In many applica...
Eva Lange, Ralf Tautenhahn, Steffen Neumann, Cleme...
BMCBI
2006
97views more  BMCBI 2006»
13 years 11 months ago
Goulphar: rapid access and expertise for standard two-color microarray normalization methods
Background: Raw data normalization is a critical step in microarray data analysis because it directly affects data interpretation. Most of the normalization methods currently used...
Sophie Lemoine, Florence Combes, Nicolas Servant, ...
BMCBI
2006
146views more  BMCBI 2006»
13 years 11 months ago
A database application for pre-processing, storage and comparison of mass spectra derived from patients and controls
Background: Statistical comparison of peptide profiles in biomarker discovery requires fast, userfriendly software for high throughput data analysis. Important features are flexib...
Mark K. Titulaer, Ivar Siccama, Lennard J. Dekker,...
INTERNET
2007
182views more  INTERNET 2007»
13 years 10 months ago
Analysis of Caching and Replication Strategies for Web Applications
Replication and caching mechanisms are often employed to enhance the performance of Web applications. In this article, we present a qualitative and quantitative analysis of state-...
Swaminathan Sivasubramanian, Guillaume Pierre, Maa...
BMCBI
2005
115views more  BMCBI 2005»
13 years 10 months ago
SUPERFICIAL - Surface mapping of proteins via structure-based peptide library design
Background: The determination of protein surfaces and the detection of binding sites are essential to our understanding of protein-protein interactions. Such binding sites can be ...
Andrean Goede, Ines S. Jaeger, Robert Preissner