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» The evolutionary capacity of protein structures
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BMCBI
2005
87views more  BMCBI 2005»
13 years 7 months ago
ProfNet, a method to derive profile-profile alignment scoring functions that improves the alignments of distantly related protei
Background: Profile-profile methods have been used for some years now to detect and align homologous proteins. The best such methods use information from the background distributi...
Tomas Ohlson, Arne Elofsson
RECOMB
2003
Springer
14 years 7 months ago
Accurate detection of very sparse sequence motifs
Protein sequence alignments are more reliable the shorter the evolutionary distance. Here, we align distantly related proteins using many closely spaced intermediate sequences as ...
Andreas Heger, Michael Lappe, Liisa Holm
TFS
2008
157views more  TFS 2008»
13 years 7 months ago
Efficient Self-Evolving Evolutionary Learning for Neurofuzzy Inference Systems
Abstract--This study proposes an efficient self-evolving evolutionary learning algorithm (SEELA) for neurofuzzy inference systems (NFISs). The major feature of the proposed SEELA i...
Cheng-Jian Lin, Cheng-Hung Chen, Chin-Teng Lin
BMCBI
2005
100views more  BMCBI 2005»
13 years 7 months ago
Evolutionary models for insertions and deletions in a probabilistic modeling framework
Background: Probabilistic models for sequence comparison (such as hidden Markov models and pair hidden Markov models for proteins and mRNAs, or their context-free grammar counterp...
Elena Rivas
BMCBI
2006
130views more  BMCBI 2006»
13 years 7 months ago
Docking protein domains in contact space
Background: Many biological processes involve the physical interaction between protein domains. Understanding these functional associations requires knowledge of the molecular str...
Stefano Lise, Alice Walker-Taylor, David T. Jones