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BMCBI
2010
201views more  BMCBI 2010»
13 years 5 months ago
IntelliGO: a new vector-based semantic similarity measure including annotation origin
Background: The Gene Ontology (GO) is a well known controlled vocabulary describing the biological process, molecular function and cellular component aspects of gene annotation. I...
Sidahmed Benabderrahmane, Malika Smaïl-Tabbon...
BCB
2010
150views Bioinformatics» more  BCB 2010»
13 years 2 months ago
Enzymatic target identification with dynamic states
As a metabolic network reaches from a state to a steady state, a subset of its fluxes gradually change. The sequence of intermediate states, called the dynamic state, shows the pa...
Bin Song, Sanjay Ranka, Tamer Kahveci
BMCBI
2011
13 years 2 months ago
Predicting functionally important SNP classes based on negative selection
Background: With the advent of cost-effective genotyping technologies, genome-wide association studies allow researchers to examine hundreds of thousands of single nucleotide poly...
Mark A. Levenstien, Robert J. Klein
BMCBI
2011
13 years 2 months ago
Estimating developmental states of tumors and normal tissues using a linear time-ordered model
Background: Tumor cells are considered to have an aberrant cell state, and some evidence indicates different development states appearing in the tumorigenesis. Embryonic developme...
Bo Zhang, Beibei Chen, Tao Wu, Zhenyu Xuan, Xiaope...
SIGOPS
2011
210views Hardware» more  SIGOPS 2011»
13 years 2 months ago
Small trusted primitives for dependable systems
Secure, fault-tolerant distributed systems are difficult to build, to validate, and to operate. Conservative design for such systems dictates that their security and fault toleran...
Petros Maniatis, Byung-Gon Chun