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BMCBI
2005
94views more  BMCBI 2005»
15 years 3 months ago
A method for finding single-nucleotide polymorphisms with allele frequencies in sequences of deep coverage
Background: The allele frequencies of single-nucleotide polymorphisms (SNPs) are needed to select an optimal subset of common SNPs for use in association studies. Sequence-based m...
Jianmin Wang, Xiaoqiu Huang
133
Voted
ICDM
2009
IEEE
149views Data Mining» more  ICDM 2009»
15 years 10 months ago
Accelerated Gradient Method for Multi-task Sparse Learning Problem
—Many real world learning problems can be recast as multi-task learning problems which utilize correlations among different tasks to obtain better generalization performance than...
Xi Chen, Weike Pan, James T. Kwok, Jaime G. Carbon...
151
Voted
BMCBI
2010
156views more  BMCBI 2010»
15 years 4 months ago
Extended morphological processing: a practical method for automatic spot detection of biological markers from microscopic images
Background: A reliable extraction technique for resolving multiple spots in light or electron microscopic images is essential in investigations of the spatial distribution and dyn...
Yoshitaka Kimori, Norio Baba, Nobuhiro Morone
KDD
2009
ACM
191views Data Mining» more  KDD 2009»
16 years 4 months ago
Efficient methods for topic model inference on streaming document collections
Topic models provide a powerful tool for analyzing large text collections by representing high dimensional data in a low dimensional subspace. Fitting a topic model given a set of...
Limin Yao, David M. Mimno, Andrew McCallum
128
Voted
BMCBI
2010
98views more  BMCBI 2010»
15 years 4 months ago
An optimized TOPS+ comparison method for enhanced TOPS models
nd: Although methods based on highly abstract descriptions of protein structures, such as VAST and TOPS, can perform very fast protein structure comparison, the results can lack a...
Mallika Veeramalai, David Gilbert, Gabriel Valient...