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BMCBI
2007
13 years 8 months ago
2007
Background: Current approaches to parameter estimation are often inappropriate or inconvenient for the modelling of complex biological systems. For systems described by nonlinear ...
BMCBI
2007
13 years 8 months ago
2007
Background: Transcriptional modules (TM) consist of groups of co-regulated genes and transcription factors (TF) regulating their expression. Two high-throughput (HT) experimental ...
BMCBI
2007
2007
Penalized likelihood for sparse contingency tables with an application to full-length cDNA libraries
13 years 8 months ago
Background: The joint analysis of several categorical variables is a common task in many areas of biology, and is becoming central to systems biology investigations whose goal is ...
BMCBI
2010
13 years 8 months ago
2010
Background: Generally speaking, different classifiers tend to work well for certain types of data and conversely, it is usually not known a priori which algorithm will be optimal ...
BMCBI
2008
13 years 8 months ago
2008
Background: Determining the function of uncharacterized proteins is a major challenge in the post-genomic era due to the problem's complexity and scale. Identifying a protein...