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BMCBI
2005
79views more  BMCBI 2005»
13 years 10 months ago
Mathematical design of prokaryotic clone-based microarrays
Background: Clone-based microarrays, on which each spot represents a random genomic fragment, are a good alternative to open reading frame-based microarrays, especially for microo...
Bart Pieterse, Elisabeth J. Quirijns, Frank H. J. ...
BMCBI
2005
169views more  BMCBI 2005»
13 years 10 months ago
Genetic interaction motif finding by expectation maximization - a novel statistical model for inferring gene modules from synthe
Background: Synthetic lethality experiments identify pairs of genes with complementary function. More direct functional associations (for example greater probability of membership...
Yan Qi 0003, Ping Ye, Joel S. Bader
BMCBI
2005
100views more  BMCBI 2005»
13 years 10 months ago
Scoredist: A simple and robust protein sequence distance estimator
Background: Distance-based methods are popular for reconstructing evolutionary trees thanks to their speed and generality. A number of methods exist for estimating distances from ...
Erik L. L. Sonnhammer, Volker Hollich
TKDE
2008
136views more  TKDE 2008»
13 years 10 months ago
Efficient Correlation Search from Graph Databases
Correlation mining has gained great success in many application domains for its ability to capture underlying dependencies between objects. However, research on correlation mining ...
Yiping Ke, James Cheng, Wilfred Ng
BMCBI
2005
178views more  BMCBI 2005»
13 years 10 months ago
A quantization method based on threshold optimization for microarray short time series
Background: Reconstructing regulatory networks from gene expression profiles is a challenging problem of functional genomics. In microarray studies the number of samples is often ...
Barbara Di Camillo, Fatima Sanchez-Cabo, Gianna To...
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