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BMCBI
2006
85views more  BMCBI 2006»
13 years 7 months ago
Use of physiological constraints to identify quantitative design principles for gene expression in yeast adaptation to heat shoc
Background: Understanding the relationship between gene expression changes, enzyme activity shifts, and the corresponding physiological adaptive response of organisms to environme...
Ester Vilaprinyó, Rui Alves, Albert Sorriba...
BMCBI
2006
101views more  BMCBI 2006»
13 years 7 months ago
How repetitive are genomes?
Background: Genome sequences vary strongly in their repetitiveness and the causes for this are still debated. Here we propose a novel measure of genome repetitiveness, the index o...
Bernhard Haubold, Thomas Wiehe
BMCBI
2006
137views more  BMCBI 2006»
13 years 7 months ago
A maximum likelihood framework for protein design
Background: The aim of protein design is to predict amino-acid sequences compatible with a given target structure. Traditionally envisioned as a purely thermodynamic question, thi...
Claudia L. Kleinman, Nicolas Rodrigue, Céci...
CN
2006
113views more  CN 2006»
13 years 7 months ago
Failure recovery for structured p2p networks: Protocol design and performance under churn
Measurement studies indicate a high rate of node dynamics in p2p systems. In this paper, we address the question of how high a rate of node dynamics can be supported by structured...
Simon S. Lam, Huaiyu Liu
CONCURRENCY
2006
142views more  CONCURRENCY 2006»
13 years 7 months ago
A Grid service broker for scheduling e-Science applications on global data Grids
: The next generation of scientific experiments and studies, popularly called e-Science, is carried out by large collaborations of researchers distributed around the world engaged ...
Srikumar Venugopal, Rajkumar Buyya, Lyle J. Winton