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» Theory and Construction of Molecular Computers
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BMCBI
2005
137views more  BMCBI 2005»
13 years 8 months ago
A configuration space of homologous proteins conserving mutual information and allowing a phylogeny inference based on pair-wise
Background: Popular methods to reconstruct molecular phylogenies are based on multiple sequence alignments, in which addition or removal of data may change the resulting tree topo...
Olivier Bastien, Philippe Ortet, Sylvaine Roy, Eri...
BMCBI
2011
13 years 3 months ago
Accurate statistics for local sequence alignment with position-dependent scoring by rare-event sampling
Background: Molecular database search tools need statistical models to assess the significance for the resulting hits. In the classical approach one asks the question how probable...
Stefan Wolfsheimer, Inke Herms, Sven Rahmann, Alex...
WABI
2009
Springer
102views Bioinformatics» more  WABI 2009»
14 years 3 months ago
A Tree Based Method for the Rapid Screening of Chemical Fingerprints
Background: The fingerprint of a molecule is a bitstring based on its structure, constructed such that structurally similar molecules will have similar fingerprints. Molecular fin...
Thomas G. Kristensen, Jesper Nielsen, Christian N....
ESA
2007
Springer
176views Algorithms» more  ESA 2007»
14 years 3 months ago
Arrangements in Geometry: Recent Advances and Challenges
We review recent progress in the study of arrangements in computational and combinatorial geometry, and discuss several open problems and areas for further research. In this talk I...
Micha Sharir
DIS
2010
Springer
13 years 7 months ago
Discovery of Conservation Laws via Matrix Search
Abstract. One of the main goals of Discovery Science is the development and analysis of methods for automatic knowledge discovery in the natural sciences. A central area of natural...
Oliver Schulte, Mark S. Drew