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BMCBI
2010
190views more  BMCBI 2010»
13 years 7 months ago
APIS: accurate prediction of hot spots in protein interfaces by combining protrusion index with solvent accessibility
Background: It is well known that most of the binding free energy of protein interaction is contributed by a few key hot spot residues. These residues are crucial for understandin...
Jun-Feng Xia, Xing-Ming Zhao, Jiangning Song, De-S...
BMCBI
2010
143views more  BMCBI 2010»
13 years 7 months ago
ETE: a python Environment for Tree Exploration
Background: Many bioinformatics analyses, ranging from gene clustering to phylogenetics, produce hierarchical trees as their main result. These are used to represent the relations...
Jaime Huerta-Cepas, Joaquín Dopazo, Toni Ga...
BMCBI
2010
163views more  BMCBI 2010»
13 years 7 months ago
Integration of open access literature into the RCSB Protein Data Bank using BioLit
Background: Biological data have traditionally been stored and made publicly available through a variety of on-line databases, whereas biological knowledge has traditionally been ...
Andreas Prlic, Marco A. Martinez, Dimitris Dimitro...
BMCBI
2010
107views more  BMCBI 2010»
13 years 7 months ago
Semantic annotation of morphological descriptions: an overall strategy
Background: Large volumes of morphological descriptions of whole organisms have been created as print or electronic text in a human-readable format. Converting the descriptions in...
Hong Cui
BMCBI
2010
188views more  BMCBI 2010»
13 years 7 months ago
CDK-Taverna: an open workflow environment for cheminformatics
Background: Small molecules are of increasing interest for bioinformatics in areas such as metabolomics and drug discovery. The recent release of large open access chemistry datab...
Thomas Kuhn, Egon L. Willighagen, Achim Zielesny, ...