An interesting and important, but largely ignored question associated with the ML method is whether there exists only a single maximum likelihood point for a given phylogenetic tr...
Radiation hybrid (RH) mapping is a somatic cell technique that is used for ordering markers along a chromosome and estimating physical distances between them. It nicely complements...
Thomas Schiex, Patrick Chabrier, Martin Bouchez, D...
Almost all medium- and large-scale businesses rely on electronic workflow systems to manage their business processes. A key challenge is to enable the easy re-use and modification...
Background: The problem of inferring the evolutionary history and constructing the phylogenetic tree with high performance has become one of the major problems in computational bi...
We propose a modified sequential quadratic programming (SQP) method for solving mixed-integer nonlinear programming problems. Under the assumption that integer variables have a s...