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BMCBI
2006
111views more  BMCBI 2006»
13 years 9 months ago
SIMMAP: Stochastic character mapping of discrete traits on phylogenies
Background: Character mapping on phylogenies has played an important, if not critical role, in our understanding of molecular, morphological, and behavioral evolution. Until very ...
Jonathan P. Bollback
BMCBI
2006
164views more  BMCBI 2006»
13 years 9 months ago
Evaluation of clustering algorithms for gene expression data
Background: Cluster analysis is an integral part of high dimensional data analysis. In the context of large scale gene expression data, a filtered set of genes are grouped togethe...
Susmita Datta, Somnath Datta
BMCBI
2006
161views more  BMCBI 2006»
13 years 9 months ago
A novel approach to phylogenetic tree construction using stochastic optimization and clustering
Background: The problem of inferring the evolutionary history and constructing the phylogenetic tree with high performance has become one of the major problems in computational bi...
Ling Qin, Yixin Chen, Yi Pan, Ling Chen
BMCBI
2006
95views more  BMCBI 2006»
13 years 9 months ago
Estimate haplotype frequencies in pedigrees
Background: Haplotype analysis has gained increasing attention in the context of association studies of disease genes and drug responsivities over the last years. The potential us...
Qiangfeng Zhang, YuZhong Zhao, Guoliang Chen, Yun ...
BMCBI
2006
192views more  BMCBI 2006»
13 years 9 months ago
Analysis of circular genome rearrangement by fusions, fissions and block-interchanges
Background: Analysis of genomes evolving via block-interchange events leads to a combinatorial problem of sorting by block-interchanges, which has been studied recently to evaluat...
Chin Lung Lu, Yen-Lin Huang, Tsui Ching Wang, Hsie...
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