Background: In testing for differential gene expression involving multiple serial analysis of gene expression (SAGE) libraries, it is critical to account for both between and with...
Serial analysis of gene expression (SAGE) is one of the most powerful tools for global gene expression profiling. It has led to several biological discoveries and biomedical appli...
Background: In gene networks, the timing of significant changes in the expression level of each gene may be the most critical information in time course expression profiles. With ...
Hao Li, Constance L. Wood, Yushu Liu, Thomas V. Ge...
Background: Affymetrix high density oligonucleotide expression arrays are widely used across all fields of biological research for measuring genome-wide gene expression. An import...
Ning Jiang, Lindsey J. Leach, Xiaohua Hu, Elena Po...
Background: Differentially expressed genes are typically identified by analyzing the variation between replicate measurements. These procedures implicitly assume that there are no...