Serial analysis of gene expression (SAGE) is one of the most powerful tools for global gene expression profiling. It has led to several biological discoveries and biomedical appli...
Background: Large-scale genomic studies often identify large gene lists, for example, the genes sharing the same expression patterns. The interpretation of these gene lists is gen...
Xin He, Moushumi Sen Sarma, Xu Ling, Brant W. Chee...
Background: The methodologies we use both enable and help define our research. However, as experimental complexity has increased the choice of appropriate methodologies has become...
James M. Eales, John W. Pinney, Robert D. Stevens,...
Background: Event sequences where different types of events often occur close together arise, e.g., when studying potential transcription factor binding sites (TFBS, events) of ce...
Background: The availability of complete genomic sequences for hundreds of organisms promises to make obtaining genome-wide estimates of substitution rates, selective constraints ...
Amy Egan, Anup Mahurkar, Jonathan Crabtree, Jonath...