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BMCBI
2010
130views more  BMCBI 2010»
13 years 8 months ago
A statistical approach to finding overlooked genetic associations
Background: Complexity and noise in expression quantitative trait loci (eQTL) studies make it difficult to distinguish potential regulatory relationships among the many interactio...
Andrew K. Rider, Geoffrey Siwo, Nitesh V. Chawla, ...
BMCBI
2010
124views more  BMCBI 2010»
13 years 8 months ago
A factor model to analyze heterogeneity in gene expression
Background: Microarray technology allows the simultaneous analysis of thousands of genes within a single experiment. Significance analyses of transcriptomic data ignore the gene d...
Yuna Blum, Guillaume Le Mignon, Sandrine Lagarrigu...
WABI
2010
Springer
170views Bioinformatics» more  WABI 2010»
13 years 7 months ago
Haplotypes versus Genotypes on Pedigrees
Abstract. Genome sequencing will soon produce haplotype data for individuals. For pedigrees of related individuals, sequencing appears to be an attractive alternative to genotyping...
Bonnie Kirkpatrick