Sciweavers

65 search results - page 6 / 13
» Topology Search over Biological Databases
Sort
View
BMCBI
2010
122views more  BMCBI 2010»
13 years 7 months ago
Fast and accurate protein substructure searching with simulated annealing and GPUs
Background: Searching a database of protein structures for matches to a query structure, or occurrences of a structural motif, is an important task in structural biology and bioin...
Alex Stivala, Peter J. Stuckey, Anthony Wirth
SIGMOD
2010
ACM
324views Database» more  SIGMOD 2010»
14 years 17 days ago
Similarity search and locality sensitive hashing using ternary content addressable memories
Similarity search methods are widely used as kernels in various data mining and machine learning applications including those in computational biology, web search/clustering. Near...
Rajendra Shinde, Ashish Goel, Pankaj Gupta, Debojy...
NAR
1998
122views more  NAR 1998»
13 years 7 months ago
The PIR-International Protein Sequence Database
The Protein Information Resource (PIR; http://wwwnbrf.georgetown.edu/pir/ ) supports research on molecular evolution, functional genomics, and computational biology by maintaining...
Winona C. Barker, John S. Garavelli, Daniel H. Haf...
ISMB
1993
13 years 9 months ago
Using Dirichlet Mixture Priors to Derive Hidden Markov Models for Protein Families
A Bayesian method for estimating the amino acid distributions in the states of a hidden Markov model (HMM) for a protein familyor the columns of a multiple alignment of that famil...
Michael Brown, Richard Hughey, Anders Krogh, I. Sa...
BMCBI
2004
96views more  BMCBI 2004»
13 years 7 months ago
A hybrid clustering approach to recognition of protein families in 114 microbial genomes
Background: Grouping proteins into sequence-based clusters is a fundamental step in many bioinformatic analyses (e.g., homology-based prediction of structure or function). Standar...
Timothy J. Harlow, J. Peter Gogarten, Mark A. Raga...