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BMCBI
2008
13 years 6 months ago
2008
Background: Amino acid sequence probability distributions, or profiles, have been used successfully to predict secondary structure and local structure in proteins. Profile models ...
BMCBI
2008
13 years 6 months ago
2008
Background: Molecular-docking-based virtual screening is an important tool in drug discovery that is used to significantly reduce the number of possible chemical compounds to be i...
BMCBI
2008
13 years 6 months ago
2008
Background: Protein-protein interactions are ubiquitous and essential for all cellular processes. High-resolution X-ray crystallographic structures of protein complexes can reveal...
BMCBI
2008
13 years 6 months ago
2008
Background: Analysis of complex samples with tandem mass spectrometry (MS/MS) has become routine in proteomic research. However, validation of database search results creates a bo...
CORR
2008
Springer
13 years 6 months ago
2008
Springer
Abstract. We propose a number of techniques for learning a global ranking from data that may be incomplete and imbalanced -- characteristics that are almost universal to modern dat...