873 search results - page 29 / 175 » Tournament scoring problem |
GECCO
2003
Springer
14 years 4 months ago
2003
Springer
For noisy optimization problems, there is generally a trade-off between the effort spent to reduce the noise (in order to allow the optimization algorithm to run properly), and t...
BMCBI
2010
2010
Orientation-dependent backbone-only residue pair scoring functions for fixed backbone protein design
13 years 11 months ago
Background: Empirical scoring functions have proven useful in protein structure modeling. Most such scoring functions depend on protein side chain conformations. However, backbone...
BMCBI
2010
13 years 11 months ago
2010
Background: The ability to design thermostable proteins is theoretically important and practically useful. Robust and accurate algorithms, however, remain elusive. One critical pr...
BMCBI
2005
13 years 11 months ago
2005
Background: The inference of homology from statistically significant sequence similarity is a central issue in sequence alignments. So far the statistical distribution function un...
BMCBI
2010
13 years 11 months ago
2010
Background: Current scoring functions are not very successful in protein-ligand binding affinity prediction albeit their popularity in structure-based drug designs. Here, we propo...