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JMLR
2012
11 years 10 months ago
Active Clustering of Biological Sequences
Given a point set S and an unknown metric d on S, we study the problem of efficiently partitioning S into k clusters while querying few distances between the points. In our model...
Konstantin Voevodski, Maria-Florina Balcan, Heiko ...
ICDT
2009
ACM
130views Database» more  ICDT 2009»
14 years 8 months ago
Towards a theory of search queries
The need to manage diverse information sources has triggered the rise of very loosely structured data models, known as "dataspace models." Such information management sy...
George H. L. Fletcher, Jan Van den Bussche, Dirk V...
CIKM
2006
Springer
13 years 11 months ago
Structure-based querying of proteins using wavelets
The ability to retrieve molecules based on structural similarity has use in many applications, from disease diagnosis and treatment to drug discovery and design. In this paper, we...
Keith Marsolo, Srinivasan Parthasarathy, Kotagiri ...
RECOMB
2005
Springer
14 years 7 months ago
Segmentation Conditional Random Fields (SCRFs): A New Approach for Protein Fold Recognition
Abstract. Protein fold recognition is an important step towards understanding protein three-dimensional structures and their functions. A conditional graphical model, i.e. segmenta...
Yan Liu, Jaime G. Carbonell, Peter Weigele, Vanath...
BMCBI
2006
143views more  BMCBI 2006»
13 years 7 months ago
IsoSVM - Distinguishing isoforms and paralogs on the protein level
Background: Recent progress in cDNA and EST sequencing is yielding a deluge of sequence data. Like database search results and proteome databases, this data gives rise to inferred...
Michael Spitzer, Stefan Lorkowski, Paul Cullen, Al...