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BMCBI
2010
156views more  BMCBI 2010»
13 years 8 months ago
Protein complex prediction via verifying and reconstructing the topology of domain-domain interactions
Background: High-throughput methods for detecting protein-protein interactions enable us to obtain large interaction networks, and also allow us to computationally identify the as...
Yosuke Ozawa, Rintaro Saito, Shigeo Fujimori, Hisa...
BMCBI
2010
160views more  BMCBI 2010»
13 years 8 months ago
Identification of functional hubs and modules by converting interactome networks into hierarchical ordering of proteins
Background: Protein-protein interactions play a key role in biological processes of proteins within a cell. Recent high-throughput techniques have generated protein-protein intera...
Young-Rae Cho, Aidong Zhang
BMCBI
2010
100views more  BMCBI 2010»
13 years 8 months ago
Using genomic signatures for HIV-1 sub-typing
Background: Human Immunodeficiency Virus type 1 (HIV-1), the causative agent of Acquired Immune Deficiency Syndrome (AIDS), exhibits very high genetic diversity with different var...
Aridaman Pandit, Somdatta Sinha
BMCBI
2010
101views more  BMCBI 2010»
13 years 8 months ago
Comparative analysis of thermophilic and mesophilic proteins using Protein Energy Networks
Background: Thermophilic proteins sustain themselves and function at higher temperatures. Despite their structural and functional similarities with their mesophilic homologues, th...
M. S. Vijayabaskar, Saraswathi Vishveshwara
BMCBI
2008
118views more  BMCBI 2008»
13 years 8 months ago
MetWAMer: eukaryotic translation initiation site prediction
Background: Translation initiation site (TIS) identification is an important aspect of the gene annotation process, requisite for the accurate delineation of protein sequences fro...
Michael E. Sparks, Volker Brendel
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