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BMCBI
2006
108views more  BMCBI 2006»
15 years 4 months ago
A new pooling strategy for high-throughput screening: the Shifted Transversal Design
Background: In binary high-throughput screening projects where the goal is the identification of low-frequency events, beyond the obvious issue of efficiency, false positives and ...
Nicolas Thierry-Mieg
BMCBI
2006
120views more  BMCBI 2006»
15 years 4 months ago
Classification of protein quaternary structure by functional domain composition
Background: The number and the arrangement of subunits that form a protein are referred to as quaternary structure. Quaternary structure is an important protein attribute that is ...
Xiaojing Yu, Chuan Wang, Yixue Li
BMCBI
2006
112views more  BMCBI 2006»
15 years 4 months ago
A correlated motif approach for finding short linear motifs from protein interaction networks
Background: An important class of interaction switches for biological circuits and disease pathways are short binding motifs. However, the biological experiments to find these bin...
Soon-Heng Tan, Hugo Willy, Wing-Kin Sung, See-Kion...
BMCBI
2006
203views more  BMCBI 2006»
15 years 4 months ago
Independent component analysis reveals new and biologically significant structures in micro array data
Background: An alternative to standard approaches to uncover biologically meaningful structures in micro array data is to treat the data as a blind source separation (BSS) problem...
Attila Frigyesi, Srinivas Veerla, David Lindgren, ...
COR
2006
82views more  COR 2006»
15 years 4 months ago
Batching work and rework processes with limited deterioration of reworkables
We study the problem of planning the production of new and recovering defective items of the same product manufactured on the same facility. Items of the product are produced in b...
Karl Inderfurth, Adam Janiak, Mikhail Y. Kovalyov,...
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