Multivariate Gaussian models are widely adopted in continuous Estimation of Distribution Algorithms (EDAs), and covariance matrix plays the essential role in guiding the evolution...
In this paper, we propose a new constrained interpolation profile (CIP) method that is stable and accurate but requires less amount of computation compared to existing CIP-based s...
Background: We propose a statistically principled baseline correction method, derived from a parametric smoothing model. It uses a score function to describe the key features of b...
Background: G-protein-coupled receptors (GPCRs) play a key role in diverse physiological processes and are the targets of almost two-thirds of the marketed drugs. The 3 D structur...
Order-preserving submatrixes (OPSMs) have been accepted as a biologically meaningful subspace cluster model, capturing the general tendency of gene expressions across a subset of ...
Byron J. Gao, Obi L. Griffith, Martin Ester, Steve...