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BMCBI
2011
13 years 23 days ago
Predicting mutually exclusive spliced exons based on exon length, splice site and reading frame conservation, and exon sequence
Background: Alternative splicing of pre-mature RNA is an important process eukaryotes utilize to increase their repertoire of different protein products. Several types of differen...
Holger Pillmann, Klas Hatje, Florian Odronitz, Bjo...
BMCBI
2011
13 years 23 days ago
SeqGene: a comprehensive software solution for mining exome- and transcriptome- sequencing data
Background: The popularity of massively parallel exome and transcriptome sequencing projects demands new data mining tools with a comprehensive set of features to support a wide r...
Xutao Deng
JAMIA
2011
98views more  JAMIA 2011»
13 years 1 days ago
Mapping clinical phenotype data elements to standardized metadata repositories and controlled terminologies: the eMERGE Network
Background Systematic study of clinical phenotypes is important for a better understanding of the genetic basis of human diseases and more effective gene-based disease management....
Jyotishman Pathak, Janey Wang, Sudha Kashyap, Meli...
SIGMOD
2012
ACM
288views Database» more  SIGMOD 2012»
11 years 11 months ago
Exploiting MapReduce-based similarity joins
Cloud enabled systems have become a crucial component to efficiently process and analyze massive amounts of data. One of the key data processing and analysis operations is the Sim...
Yasin N. Silva, Jason M. Reed
STOC
2012
ACM
251views Algorithms» more  STOC 2012»
11 years 11 months ago
Minimax option pricing meets black-scholes in the limit
Option contracts are a type of financial derivative that allow investors to hedge risk and speculate on the variation of an asset’s future market price. In short, an option has...
Jacob Abernethy, Rafael M. Frongillo, Andre Wibiso...