We have developed a calculus, called Ipi, for describing the aberrance in biological models. Our approach extends the traditional pi calculus to handle aberrant process in the sign...
Min Zhang, Guoqiang Li, Yuxi Fu, Zhizhou Zhang, Li...
The pi calculus has been applied to modelling biochemical networks. In these applications, the modelling is done without considerations to exceptions. The Ipi calculus, the Interfe...
Min Zhang, Guoqiang Li, Yuxi Fu, Zhizhou Zhang, Li...
Background: DNA copy number aberration (CNA) is very important in the pathogenesis of tumors and other diseases. For example, CNAs may result in suppression of anti-oncogenes and ...
Background: Elucidating the exact relationship between gene copy number and expression would enable identification of regulatory mechanisms of abnormal gene expression and biologi...
Background: Post-translational modifications (PTMs) have a key role in regulating cell functions. Consequently, identification of PTM sites has a significant impact on understandi...