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BMCBI
2010
13 years 7 months ago
2010
Background: The decrease in cost for sequencing and improvement in technologies has made it easier and more common for the re-sequencing of large genomes as well as parallel seque...
BMCBI
2010
13 years 7 months ago
2010
Background: There is an increasing number of proteins with known structure but unknown function. Determining their function would have a significant impact on understanding diseas...
BMCBI
2008
13 years 7 months ago
2008
Background: Transcription factors (TFs) are core functional proteins which play important roles in gene expression control, and they are key factors for gene regulation network co...
BMCBI
2008
13 years 7 months ago
2008
Background: Modern omics research involves the application of high-throughput technologies that generate vast volumes of data. These data need to be pre-processed, analyzed and in...
BMCBI
2008
13 years 7 months ago
2008
teps. First, we abstracted protein interactions onto orthologous cluster links. For a given source interaction, if both proteins belonged to a cluster, we constructed a link betwee...