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BMCBI
2010
191views more  BMCBI 2010»
13 years 10 months ago
Colonyzer: automated quantification of micro-organism growth characteristics on solid agar
Background: High-throughput screens comparing growth rates of arrays of distinct micro-organism cultures on solid agar are useful, rapid methods of quantifying genetic interaction...
Conor Lawless, Darren J. Wilkinson, Alexander Youn...
BMCBI
2010
106views more  BMCBI 2010»
13 years 10 months ago
A computational evaluation of over-representation of regulatory motifs in the promoter regions of differentially expressed genes
Background: Observed co-expression of a group of genes is frequently attributed to co-regulation by shared transcription factors. This assumption has led to the hypothesis that pr...
Guofeng Meng, Axel Mosig, Martin Vingron
BMCBI
2010
110views more  BMCBI 2010»
13 years 10 months ago
Discovering local patterns of co - evolution: computational aspects and biological examples
Background: Co-evolution is the process in which two (or more) sets of orthologs exhibit a similar or correlative pattern of evolution. Co-evolution is a powerful way to learn abo...
Tamir Tuller, Yifat Felder, Martin Kupiec
BIOINFORMATICS
2008
106views more  BIOINFORMATICS 2008»
13 years 10 months ago
Small RNA gene identification and mRNA target predictions in bacteria
Motivation: Bacterial small ribonucleic acids (sRNAs) that are not ribosomal and transfer or messenger RNAs were initially identified in the sixties whereas their molecular functi...
Christophe Pichon, Brice Felden
BMCBI
2010
141views more  BMCBI 2010»
13 years 10 months ago
Computing and visually analyzing mutual information in molecular co-evolution
Background: Selective pressure in molecular evolution leads to uneven distributions of amino acids and nucleotides. In fact one observes correlations among such constituents due t...
Sebastian Bremm, Tobias Schreck, Patrick Boba, Ste...