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C5
2004
IEEE
15 years 8 months ago
Scratch: A Sneak Preview
information technologies as "the ability to reformulate knowledge, to express oneself creatively and appropriately, and to produce and generate information (rather than simply...
John Maloney, Leo Burd, Yasmin B. Kafai, Natalie R...
FMSB
2008
129views Formal Methods» more  FMSB 2008»
15 years 6 months ago
Rule-Based Modelling, Symmetries, Refinements
Rule-based modelling is particularly effective for handling the highly combinatorial aspects of cellular signalling. The dynamics is described in terms of interactions between part...
Vincent Danos, Jérôme Feret, Walter F...
BCS
2008
15 years 6 months ago
Beatbox - A Computer Simulation Environment for Computational Biology of the Heart
Despite over a century's study, the trigger mechanisms of cardiac arrhythmias are poorly understood. Even modern experimental methods do not provide sufficient temporal and s...
Ross McFarlane, Irina V. Biktasheva
BMCBI
2010
133views more  BMCBI 2010»
15 years 4 months ago
New components of the Dictyostelium PKA pathway revealed by Bayesian analysis of expression data
Background: Identifying candidate genes in genetic networks is important for understanding regulation and biological function. Large gene expression datasets contain relevant info...
Anup Parikh, Eryong Huang, Christopher Dinh, Blaz ...
BMCBI
2010
97views more  BMCBI 2010»
15 years 4 months ago
Dual-functioning transcription factors in the developmental gene network of Drosophila melanogaster
Background: Quantitative models for transcriptional regulation have shown great promise for advancing our understanding of the biological mechanisms underlying gene regulation. Ho...
Denis C. Bauer, Fabian A. Buske, Timothy L. Bailey