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BMCBI
2006
132views more  BMCBI 2006»
13 years 9 months ago
Genome-wide DNA polymorphism analyses using VariScan
Background: DNA sequence polymorphisms analysis can provide valuable information on the evolutionary forces shaping nucleotide variation, and provides an insight into the function...
Stephan Hutter, Albert J. Vilella, Julio Rozas
BMCBI
2006
45views more  BMCBI 2006»
13 years 9 months ago
A simple spreadsheet-based, MIAME-supportive format for microarray data: MAGE-TAB
Background: Sharing of microarray data within the research community has been greatly facilitated by the development of the disclosure and communication standards MIAME and MAGEML...
Tim F. Rayner, Philippe Rocca-Serra, Paul T. Spell...
BMCBI
2006
117views more  BMCBI 2006»
13 years 9 months ago
A method for estimation of elasticities in metabolic networks using steady state and dynamic metabolomics data and linlog kineti
Background: Dynamic modeling of metabolic reaction networks under in vivo conditions is a crucial step in order to obtain a better understanding of the (dis)functioning of living ...
I. Emrah Nikerel, Wouter A. van Winden, Walter M. ...
BMCBI
2006
130views more  BMCBI 2006»
13 years 9 months ago
An accurate and interpretable model for siRNA efficacy prediction
Background: The use of exogenous small interfering RNAs (siRNAs) for gene silencing has quickly become a widespread molecular tool providing a powerful means for gene functional s...
Jean-Philippe Vert, Nicolas Foveau, Christian Laja...
BMCBI
2006
136views more  BMCBI 2006»
13 years 9 months ago
EMD: an ensemble algorithm for discovering regulatory motifs in DNA sequences
Background: Understanding gene regulatory networks has become one of the central research problems in bioinformatics. More than thirty algorithms have been proposed to identify DN...
Jianjun Hu, Yifeng D. Yang, Daisuke Kihara
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