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» Unfolding of Microarray Data
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EMO
2005
Springer
108views Optimization» more  EMO 2005»
14 years 1 months ago
Multi-objective Model Optimization for Inferring Gene Regulatory Networks
With the invention of microarray technology, researchers are able to measure the expression levels of ten thousands of genes in parallel at various time points of a biological proc...
Christian Spieth, Felix Streichert, Nora Speer, An...
WABI
2001
Springer
162views Bioinformatics» more  WABI 2001»
14 years 9 days ago
A Simple Hyper-Geometric Approach for Discovering Putative Transcription Factor Binding Sites
A central issue in molecular biology is understanding the regulatory mechanisms that control gene expression. The recent flood of genomic and postgenomic data opens the way for co...
Yoseph Barash, Gill Bejerano, Nir Friedman
BMCBI
2005
114views more  BMCBI 2005»
13 years 7 months ago
Quality determination and the repair of poor quality spots in array experiments
Background: A common feature of microarray experiments is the occurence of missing gene expression data. These missing values occur for a variety of reasons, in particular, becaus...
Brian D. M. Tom, Walter R. Gilks, Elizabeth T. Bro...
BMCBI
2010
161views more  BMCBI 2010»
13 years 8 months ago
GATExplorer: Genomic and Transcriptomic Explorer; mapping expression probes to gene loci, transcripts, exons and ncRNAs
Background: Genome-wide expression studies have developed exponentially in recent years as a result of extensive use of microarray technology. However, expression signals are typi...
Alberto Risueño, Celia Fontanillo, Marcel E...
BMCBI
2008
138views more  BMCBI 2008»
13 years 8 months ago
Combining transcriptional datasets using the generalized singular value decomposition
Background: Both microarrays and quantitative real-time PCR are convenient tools for studying the transcriptional levels of genes. The former is preferable for large scale studies...
Andreas W. Schreiber, Neil J. Shirley, Rachel A. B...