Background: A typical step in the analysis of gene expression data is the determination of clusters of genes that exhibit similar expression patterns. Researchers are confronted w...
Evert-Jan Blom, Sacha A. F. T. van Hijum, Klaas J....
We studied 1372 LacI-family transcription factors and their 4484 DNA binding sites using machine learning algorithms and feature selection techniques. The Naive Bayes classifier a...
In this study, we seek to develop a predictive model for finding the strength of binding between a particular transcription factor (TF) variant and a particular DNA target variant...
Background: This paper addresses the problem of recognising DNA cis-regulatory modules which are located far from genes. Experimental procedures for this are slow and costly, and ...
Irina I. Abnizova, Rene te Boekhorst, Klaudia Walt...
Background: Discovery of precise specificity of transcription factors is an important step on the way to understanding the complex mechanisms of gene regulation in eukaryotes. Rec...