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» Using Multiple Alignments to Improve Gene Prediction
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BMCBI
2005
87views more  BMCBI 2005»
13 years 7 months ago
Efficient decoding algorithms for generalized hidden Markov model gene finders
Background: The Generalized Hidden Markov Model (GHMM) has proven a useful framework for the task of computational gene prediction in eukaryotic genomes, due to its flexibility an...
William H. Majoros, Mihaela Pertea, Arthur L. Delc...
SC
2003
ACM
14 years 20 days ago
A Million-Fold Speed Improvement in Genomic Repeats Detection
This paper presents a novel, parallel algorithm for generating top alignments. Top alignments are used for finding internal repeats in biological sequences like proteins and gene...
John W. Romein, Jaap Heringa, Henri E. Bal
KDD
2004
ACM
142views Data Mining» more  KDD 2004»
14 years 7 months ago
Meta-classification of Multi-type Cancer Gene Expression Data
Massive publicly available gene expression data consisting of different experimental conditions and microarray platforms introduce new challenges in data mining when integrating m...
Benny Y. M. Fung, Vincent T. Y. Ng
ISMB
1994
13 years 8 months ago
An Improved System for Exon Recognition and Gene Modeling in Human DNA Sequence
A new version of the GRAIL system (Uberbacher and Mural, 1991; Mural et al., 1992; Uberbacher et al., 1993), called GRAILII, has recently been developed (Xu et al., 1994). GRAILII...
Yin Xu, J. Ralph Einstein, Richard J. Mural, Manes...
RECOMB
2003
Springer
14 years 7 months ago
Whole-genome comparative annotation and regulatory motif discovery in multiple yeast species
In [13] we reported the genome sequences of S. paradoxus, S. mikatae and S. bayanus and compared these three yeast species to their close relative, S. cerevisiae. Genome-wide comp...
Manolis Kamvysselis, Nick Patterson, Bruce Birren,...