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» Using Multiple Alignments to Improve Gene Prediction
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134
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BIBE
2005
IEEE
15 years 9 months ago
Improved Phylogenetic Motif Detection Using Parsimony
We have recently demonstrated (La et al, Proteins, 58:2005) that sequence fragments approximating the overall familial phylogeny, called phylogenetic motifs (PMs), represent a pro...
Usman Roshan, Dennis R. Livesay, David La
134
Voted
BMCBI
2006
100views more  BMCBI 2006»
15 years 3 months ago
Using the nucleotide substitution rate matrix to detect horizontal gene transfer
Background: Horizontal gene transfer (HGT) has allowed bacteria to evolve many new capabilities. Because transferred genes perform many medically important functions, such as conf...
Micah Hamady, M. D. Betterton, Rob Knight
132
Voted
BMCBI
2006
144views more  BMCBI 2006»
15 years 3 months ago
More robust detection of motifs in coexpressed genes by using phylogenetic information
Background: Several motif detection algorithms have been developed to discover overrepresented motifs in sets of coexpressed genes. However, in a noisy gene list, the number of ge...
Pieter Monsieurs, Gert Thijs, Abeer A. Fadda, Sigr...
CICLING
2010
Springer
14 years 10 months ago
A Chunk-Driven Bootstrapping Approach to Extracting Translation Patterns
Abstract. We present a linguistically-motivated sub-sentential alignment system that extends the intersected IBM Model 4 word alignments. The alignment system is chunk-driven and r...
Lieve Macken, Walter Daelemans
134
Voted
BMCBI
2005
125views more  BMCBI 2005»
15 years 3 months ago
Multiple sequence alignments of partially coding nucleic acid sequences
Background: High quality sequence alignments of RNA and DNA sequences are an important prerequisite for the comparative analysis of genomic sequence data. Nucleic acid sequences, ...
Roman R. Stocsits, Ivo L. Hofacker, Claudia Fried,...