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» Using Multiple Alignments to Improve Gene Prediction
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BIOCOMP
2009
15 years 4 months ago
Consensus RNA Secondary Structure Prediction by Ranking k-Length Stems
The accurate computational prediction of RNA secondary structures is a difficult task, but an important one, since RNA structure is usually more evolutionarily conserved than prima...
Denise Y. F. Mak, Gary Benson
144
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BMCBI
2005
102views more  BMCBI 2005»
15 years 3 months ago
Genome-wide identification of the regulatory targets of a transcription factor using biochemical characterization and computatio
Background: A major challenge in computational genomics is the development of methodologies that allow accurate genome-wide prediction of the regulatory targets of a transcription...
Emmitt R. Jolly, Chen-Shan Chin, Ira Herskowitz, H...
150
Voted
JCB
2006
129views more  JCB 2006»
15 years 3 months ago
GenRate: A Generative Model that Reveals Novel Transcripts in Genome-Tiling Microarray Data
Genome-wide microarray designs containing millions to hundreds of millions of probes are available for a variety of mammals, including mouse and human. These genome tiling arrays ...
Brendan J. Frey, Quaid Morris, Timothy R. Hughes
160
Voted
BMCBI
2004
205views more  BMCBI 2004»
15 years 3 months ago
A combinational feature selection and ensemble neural network method for classification of gene expression data
Background: Microarray experiments are becoming a powerful tool for clinical diagnosis, as they have the potential to discover gene expression patterns that are characteristic for...
Bing Liu, Qinghua Cui, Tianzi Jiang, Songde Ma
152
Voted
BMCBI
2005
151views more  BMCBI 2005»
15 years 3 months ago
ProMiner: rule-based protein and gene entity recognition
Background: Identification of gene and protein names in biomedical text is a challenging task as the corresponding nomenclature has evolved over time. This has led to multiple syn...
Daniel Hanisch, Katrin Fundel, Heinz-Theodor Mevis...