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RECOMB
2002
Springer
14 years 7 months ago
Combining pairwise sequence similarity and support vector machines for remote protein homology detection
One key element in understanding the molecular machinery of the cell is to understand the meaning, or function, of each protein encoded in the genome. A very successful means of i...
Li Liao, William Stafford Noble
BMCBI
2010
151views more  BMCBI 2010»
13 years 7 months ago
Using diffusion distances for flexible molecular shape comparison
Background: Many molecules are flexible and undergo significant shape deformation as part of their function, and yet most existing molecular shape comparison (MSC) methods treat t...
Yu-Shen Liu, Qi Li, Guo-Qin Zheng, Karthik Ramani,...
ICPPW
2009
IEEE
13 years 5 months ago
A Scalable Parallel Approach for Peptide Identification from Large-Scale Mass Spectrometry Data
Identifying peptides, which are short polymeric chains of amino acid residues in a protein sequence, is of fundamental importance in systems biology research. The most popular appr...
Gaurav Ramesh Kulkarni, Ananth Kalyanaraman, Willi...
CSR
2006
Springer
13 years 11 months ago
Fast Motif Search in Protein Sequence Databases
Regular expression pattern matching is widely used in computational biology. Searching through a database of sequences for a motif (a simple regular expression), or its variations...
Elena Zheleva, Abdullah N. Arslan
BMCBI
2008
130views more  BMCBI 2008»
13 years 7 months ago
A database of phylogenetically atypical genes in archaeal and bacterial genomes, identified using the DarkHorse algorithm
Background: The process of horizontal gene transfer (HGT) is believed to be widespread in Bacteria and Archaea, but little comparative data is available addressing its occurrence ...
Sheila Podell, Terry Gaasterland, Eric E. Allen