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BMCBI
2010
91views more  BMCBI 2010»
13 years 8 months ago
Algorithm-driven Artifacts in median polish summarization of Microarray data
Background: High-throughput measurement of transcript intensities using Affymetrix type oligonucleotide microarrays has produced a massive quantity of data during the last decade....
Federico M. Giorgi, Anthony M. Bolger, Marc Lohse,...
BMCBI
2008
145views more  BMCBI 2008»
13 years 8 months ago
The contrasting properties of conservation and correlated phylogeny in protein functional residue prediction
Background: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are ...
Jonathan R. Manning, Emily R. Jefferson, Geoffrey ...
IMC
2006
ACM
14 years 2 months ago
Quantifying path exploration in the internet
A number of previous measurement studies [10, 12, 17] have shown the existence of path exploration and slow convergence in the global Internet routing system, and a number of prot...
Ricardo V. Oliveira, Beichuan Zhang, Dan Pei, Rafi...
ICALP
2001
Springer
14 years 1 months ago
Permutation Editing and Matching via Embeddings
Abstract. If the genetic maps of two species are modelled as permutations of (homologous) genes, the number of chromosomal rearrangements in the form of deletions, block moves, inv...
Graham Cormode, S. Muthukrishnan, Süleyman Ce...
BMCBI
2006
134views more  BMCBI 2006»
13 years 8 months ago
A statistical score for assessing the quality of multiple sequence alignments
Background: Multiple sequence alignment is the foundation of many important applications in bioinformatics that aim at detecting functionally important regions, predicting protein...
Virpi Ahola, Tero Aittokallio, Mauno Vihinen, Esa ...